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Sodium Alginate

​CAS No.: 9005-38-3
Molecular formula: C5H7O4COONa

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Related Categories: Inorganic Compounds and Salts; Feed Additives; Pharmaceutical Raw Materials; Carbohydrates; Plant Biochemical Extracts; Medicines; APIs; Pharmaceutical Excipients; Nutrients; Foods Gels Thickeners Suspending Agents;




Storage conditions

Store at RT.


Slowly soluble in water forming a viscous, colloidal solution, practically insoluble in ethanol (96 per cent).




White to Off-white

PH value

6.0-8.0 (10mg/mL in H2O)

Water solubility

Soluble in water. Insoluble in alcohol, chloroform and ether.






Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.

CAS database

9005-38-3(CAS DataBase Reference)


Sodium alginate is a by-product of the extraction of iodine and mannitol from kelp or sargasso of brown algae, and its molecule is composed of β-D-mannuronic acid (M) and α-L-Gullo. The uronic acid (α-L-guluronic, G) is formed by a (1→4) bond. The aqueous solution of sodium alginate has a high viscosity and has been used as a thickener, stabilizer, emulsifier, etc. for foods. Sodium alginate is a non-toxic food that has been included in the United States Pharmacopoeia as early as 1938. Sodium alginate contains a large amount of -COO-, which can exhibit polyanionic behavior in aqueous solution and has certain adhesion, and can be used as a drug carrier for treating mucosal tissues. Under acidic conditions, -COO- is converted to -COOH, the degree of ionization is lowered, the hydrophilicity of sodium alginate is lowered, the molecular chain is shrunk, and when the pH is increased, the -COOH group is continuously dissociated, and the hydrophilicity of sodium alginate Increased sex and molecular chain stretching. Therefore, sodium alginate has significant pH sensitivity. Sodium alginate can rapidly form a gel under extremely mild conditions. When cations such as Ca2+ and Sr2+ are present, Na+ on the G unit undergoes ion exchange reaction with divalent cations, and G units are stacked to form a crosslinked network structure, thereby forming Hydrogels. The conditions under which sodium alginate forms a gel are mild, which avoids the inactivation of sensitive substances such as sensitive drugs, proteins, cells and enzymes. Due to these excellent properties, sodium alginate has been widely used in the food industry and medicine.

Chemical properties

Colorless or light yellow filament granules or powdered solids. Insoluble in organic solvents such as ethanol, ether and chloroform.


1. Used as a sizing agent and printing paste for textiles, and used as a thickener, stabilizer and emulsifier in the food industry.

2. It is used as an emulsion stabilizer and thickener. It can be used in various foods in China and used in an appropriate amount according to production needs.

3. It is used to increase blood volume and maintain blood pressure, to eliminate histamine toxoids caused by burns, traumatic blood loss, stability of circulatory system before and after surgery, massive hemorrhagic shock, burn shock, high fever and acute dysentery. good. It also has the effect of excreting cholesterol outside the body, inhibiting the absorption of Pb, Cd, and Sr by the human body, and protecting the gastrointestinal tract, the whole intestine, losing weight, and lowering blood sugar.

4. It is mainly used as a suspending agent, an emulsifier, a thickener, a capsule of a microcapsule, etc. in the medicament.

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