Related Categories: APIs; anti-tumor; pharmaceutical raw materials; anti-tumor; cell cycle non-specific drugs
340 °C (dec.)(lit.)
Store at RT
Soluble in DMF. Insoluble in most common solvents
<0.1 g/100 mL at 19 ºC
Stable. Incompatible with oxidizing agents, aluminium, antioxidants.
15663-27-1(CAS DataBase Reference)
Orange or yellow crystalline powder. Melting point 268-272 ° C (decomposition). Slightly soluble in water, soluble in dimethylformamide. It can be gradually converted into trans and hydrolyzed in aqueous solution.
The product binds to DNA, causing cross-linking, thereby disrupting DNA function and inhibiting cell mitosis, a cell-specific drug. The product has a wide anti-tumor spectrum and is used for head and neck squamous cell carcinoma, ovarian cancer, embryonic cell carcinoma, spermatogonia, lung cancer, thyroid cancer, lymphosarcoma and reticular cell sarcoma.