Related categories: anti-tumor drugs and immunosuppressants; pharmaceutical raw materials; small molecule inhibitors; natural products; anti-tumor; API; platinum; broad-spectrum anti-tumor drugs
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Sparingly soluble in water, very slightly soluble in acetone and in ethanol (96 per cent).
Soluble in water.
Stable. Incompatible with strong oxidizing agents.
White flocculent loose powder, sponge-like mass, odorless. soluble in water. It is easy to break down when it is light.
Second generation platinum complex anti-tumor drugs. The anti-tumor spectrum and anti-tumor activity are similar to those of cisplatin, but the water solubility is better than that of cisplatin and the toxicity to the kidney is also low. It has good curative effect on small cell lung cancer, ovarian cancer, head and neck squamous cell carcinoma, testicular tumor, malignant lymphoma, etc. It can also be used for cervical cancer and bladder cancer.
The scope of action of carboplatin is generally similar to that of cisplatin. The main advantage of this new analog is its difference in toxicity. Currently, carboplatin is used as a palliative treatment for recurrent ovarian cancer, including patients who have previously used cisplatin. Clinical studies have also shown that carboplatin can produce an objective response to head and neck tumors, small cell lung cancer, and testicular seminoma.