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2,4,7-Diamino-6-Phenyl Pteridine

CAS No.: 396-01-0
Molecular formula: C12H11N7
Molecular weight: 253.26
Related categories: DYRENIUM; Other APIs; pharmaceutical intermediates; small molecule inhibitors; pharmaceutical raw materials; diuretic bulk drugs
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396-01-0

Nature

Melting point

316°C

Boiling point

386.46°C (rough estimate)

Density

1.3215 (rough estimate)

Refractive index

1.8260 (estimate)

Flash point

11 °C

Storage conditions

2-8°C

Solubility

formic acid: soluble200 mg + 4 mL warm Formic Acid, clear, yellow-green

Acidity coefficient (pKa)

6.2(at 25℃)

Water solubility

<0.1 G/100 ML AT 20 ºC

Merck

14,9599

BRN

266723

InChIKey

FNYLWPVRPXGIIP-UHFFFAOYSA-N

CAS database

396-01-0(CAS DataBase Reference)


Traits

It is a yellow crystalline powder, odorless or almost odorless and tasteless. Insoluble in water, ethanol, chloroform or ether, very slightly soluble in glacial acetic acid, almost insoluble in dilute mineral acids.

396-01-0


Chemical properties

Yellow crystalline powder. The temperature of 316 ° C (327 ° C), very slightly soluble in glacial acetic acid, almost insoluble in water, ethanol, chloroform. Odorless or almost odorless, tasteless.

Use


A weak diuretic. The effect is rapid and short-lived. Diuresis begins 2 hours after oral administration, peaks at 6 hours, and lasts for 8-12 hours. It is clinically used for refractory edema or ascites caused by heart failure, liver cirrhosis and chronic nephritis. It is also used for the production of hydrochlorothiazide or spironolactone. Case. This product has the effect of eliminating uric acid and is suitable for the treatment of gout.


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