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L(-)-Epinephrine

​CAS No.: 51-43-4
Molecular formula: C9H13NO3
Molecular weight: 183.2
Related categories:Pharmaceutical raw materials
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Properties:

It is white or off-white crystalline powder, odorless and bitter. Very slightly soluble in water, insoluble in organic solvents such as ethanol and chloroform, soluble in mineral acid or sodium hydroxide solution. It is unstable in a neutral or alkaline aqueous solution, and the saturated aqueous solution is weakly alkaline. Commonly used in its hydrochloride, soluble in water, 0.1% aqueous solution pH is 2.5 ~ 5.0, this product and its salt in the case of oxides, alkalis, light and heat, are easily decomposed and metamorphosed into pink to brownish red.


Organogenesis

Adrenalin is secreted by the adrenal gland. The adrenal gland is a very important endocrine organ of the human body. It is called the adrenal gland because it is located above the kidneys on both sides. The adrenal gland is located one above the other, located above the kidney, and is jointly wrapped by the renal fascia and adipose tissue. The left adrenal gland is half-moon shaped and the right adrenal gland is triangular. The total weight of the adrenal glands is about 30 g. Viewed from the side, the glands are divided into two parts: the adrenal cortex and the adrenal medulla. The surrounding part is the cortex and the inner part is the medulla. The two are different in their occurrence, structure and function. They are actually two endocrine glands.

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Chemical properties:

White crystalline powder. The temperature of 213 ° C (decomposition), soluble in mineral acid and alkali hydroxide solution, slightly soluble in water, insoluble in alcohol, ether, acetone, chloroform. Odorless, bitter. The air is exposed and the light is getting darker.


Overview:

Adrenaline, also known as accessory renin and para-renine, is extracted from the adrenal medulla of livestock (bovine, sheep) or artificially synthesized. It is a white or off-white crystalline powder and is excited by α and β receptors. effect. Adrenalin is a hormone secreted by chromaffin cells in the adrenal medulla. Mainly involved in the regulation of the sympathetic nervous system.


Nature:

Melting point

215 °C (dec.)(lit.)

Specific rotation

-51.5 º (c=4, 1M HCl, dry sub)

Boiling point

316.88°C (rough estimate)

Density

1.1967 (rough estimate)

Refractive index

-51.5 ° (C=4, 1mol/L HCl)

Storage conditions

2-8°C

Solubility

Practically insoluble in water, in ethanol (96 per cent) and in methylene chloride. It dissolves in hydrochloric acid.

form

Fine Crystalline Powder

Acidity coefficient (pKa)

8.66(at 25℃)

colour

White to light beige

Water solubility

<0.01 g/100 mL at 18 ºC

Sensitivity

Air & Light Sensitive

Merck

14,3619

BRN

2368277

stability

Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive.

CAS database

51-43-4(CAS DataBase Reference)

NIST Chemical Information

L-adrenaline(51-43-4)

EPA chemical information

1,2-Benzenediol, 4-[(1R)-1-hydroxy-2-(methylamino) ethyl]-(51-43-4)


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