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Doxazosin Mesylate

CAS No.: 77883-43-3
Molecular formula: C24H29N5O8S
Molecular weight: 547.58
Related categories:Pharmaceutical raw materials; pharmaceutical intermediates; small molecule inhibitors
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77883-43-3

Appearance:

White or off-white crystalline powder Related substances: ≤1.0% dry weight loss: ≤1.0% ignition residue: ≤0.1% heavy metal: ≤10ppm content: ≥99.0%


Uses:

Primary mild-to-moderate hypertension, and hypertensive patients with benign prostatic hypertrophy. For patients who have difficulty controlling blood pressure with a single drug, doxazine can be combined with thiazide diuretics and beta-blockers, calcium antagonists or angiotensin converting enzyme inhibitors.


Melting point

275-277°C

Storage conditions

Desiccate at RT

Solubility

Slightly soluble in water, soluble in a mixture of 15 volumes of water and 35 volumes of tetrahydrofuran, slightly soluble in methanol, practically insoluble in acetone. It shows polymorphism (5.9), some forms may be hygroscopic

form

powder

colour

white

stability

Protect from light

InChIKey

VJECBOKJABCYMF-UHFFFAOYSA-N

CAS database

77883-43-3(CAS DataBase Reference)


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