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Aminophenazone

CAS No.:7757-83-7
White leaf crystal or crystalline powder. Odorless, slightly bitter taste. It is stable in the air, but it will deteriorate in daylight....

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When there is moisture,  it will easily react with weak oxidants. Soluble in alcohol, chloroform, benzene and ether, soluble in water. The solubility in water increases with the addition of sodium benzoate. The aqueous solution is weakly alkaline to litmus. The melting point is  107-109 ° C.


Melting point

107-109 °C(lit.)

Boiling point

373.38°C (rough estimate)

Density

1.0744 (rough estimate)

Refractive index

1.6140 (estimate)

Storage conditions

Refrigerator

Acidity coefficient (pKa)

pKa 5.0 (Uncertain)

form

Crystalline Powder, Crystals and/or Chunks

colour

Off-white to brownish

Water solubility

5.55 g/100 mL

Sensitivity

Air & Light Sensitive

Merck

14,474


USE

Antipyretic and analgesic for fever, headache, joint pain, neuralgia, dysmenorrhea and active rheumatism. Aminopyrine is a pyrazolone non-steroidal anti-inflammatory drug with strong antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects. However, due to serious adverse reactions, such as agranulocytosis, aplastic anemia and so on. Therefore, the clinical application has been decreasing and gradually phasing out. Aminopyrine can also be used as an analytical reagent for the determination of lanthanum, cerium, bromine, cadmium, chlorine, cobalt, ketone, cyanide, gold, iron iodic acid, lead, nickel, nitric acid, nitrite, bismuth, nitrogen oxides, Palladium, platinum, silver and zinc.


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